Cannabinoid Receptor 1
A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds to cannabinoid receptors (CBR) and prevents their activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs. The discovery of the endocannabinoid system led to the development of CB1 receptor antagonists
Cannabinoid Receptor 2
Cannabinoid receptors are of a class of cell membrane receptors under the G protein-coupled receptor superfamily. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as Cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and plant cannabinoids are lipophilic, such as fat soluble compounds
Sabinene is a bicyclic monoterpene whose aromas are reminiscent of the holidays (pines, oranges, spices). Results of an ongoing study by Valente et al suggest that sabinene should be explored further as a natural source of new antioxidant and anti-inflammatory drugs for the development of food supplements, nutraceuticals or plant-based medicines.
Sabinene occurs in many plants, including Norway spruce, black pepper, basil and Myristica fragrans (an evergreen indigenous to the Moluccas)—the Spice Islands of Indonesia. The seeds of the Myristica fragrans are the world’s main source of nutmeg. Sabinene exists as (+)- and (–)-enantiomers.
All About Sabinene
Sabinene which is also known as Sabinen or Sabenene is a compound present in a variety of plants such as black pepper, nutmeg, Norway spruce and Holm oak among others. It can also be derived from tea tree oil in small concentrations and it’s a key ingredient of carrot seed oil. It is anti inflammatory and anti bacterial in nature and therefore, it has found a variety of beneficial uses.
As far as the attributes of this unsaturated terpenoid is concerned, it has a spicy and woody smell. In fact, it is the reason behind the spicy and hotness element of black pepper. It is also one of the constituents that are responsible for adding flavor to carrots. The earthy and green flavor of the carrot is due to significant presence of sabinene compound in it. It is also used as an additive in perfumes.
One of the most beneficial properties of this compound is that it is anti-inflammatory in nature. It also has antimicrobial as well as anti fungal properties. A number of research studies have confirmed that this compound exhibits a strong anti-inflammatory activity. It may also be used for treatment of skin inflammation. It’s presence in tea tree oil adds to the anti bacterial and anti fungal properties of this essential oil.
As this compound is found in black pepper as well as tea tree essential oil, it adds to the anti-inflammatory and anti bacterial nature of these essential oils. Tea tree oil has been found to be exceptional for treatment of various skin problems such as fungus. For treatment of fungus, you should take only a dab of the tea tree essential oil on a cotton swab and apply it to the fungal infection. Essential oils contain a variety of compounds such as Sabinene which lead to provide antibacterial, anti-fungal and various other beneficial properties of essential oils.
Overall, there are a number of other benefits of essential oils. However, it is important that you buy essential oils only from a well-known and reputed brand. There are a number of different brands of essential oils available in the market but all the oils are not pure. Before buying, you should check the ratings and reviews of various brands to make sure that you are buying pure essential oils. Also, essential oils should be used in the prescribed manner these are concentrated oils and using a lot may lead to some unexpected problems.